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Giants aim to stop losing streak in matchup with the Diamondbacks

San Francisco Giants (45-41, third in the NL West) vs. Arizona Diamondbacks (43-42, fourth in the NL West) Phoenix; Wednesday, 9:40 p.m. EDT PITCHING PROBABLES: Giants: Landen Roupp (6-5, 3.54 ERA, 1.

Los Angeles Dodgers and Chicago White Sox meet in game 2 of series

Chicago White Sox (28-57, fifth in the AL Central) vs. Los Angeles Dodgers (54-32, first in the NL West) Los Angeles; Wednesday, 10:10 p.m. EDT PITCHING PROBABLES: White Sox: Sean Burke (4-7, 4.22 ERA, 1.

Phillies play the Padres with 1-0 series lead

San Diego Padres (45-39, second in the NL West) vs. Philadelphia Phillies (50-35, first in the NL East) Philadelphia; Wednesday, 1:05 p.m. EDT PITCHING PROBABLES: Padres: Nick Pivetta (8-2, 3.36 ERA, 1.

Rays host Athletics, look to end home skid

Athletics (36-52, fifth in the AL West) vs. Tampa Bay Rays (47-39, third in the AL East) Tampa, Florida; Wednesday, 12:10 p.m. EDT PITCHING PROBABLES: Athletics: Mitch Spence (2-3, 3.82 ERA, 1.30 WHIP, 55 strikeouts); Rays: Ryan Pepiot (5-6, 3.

Pirates look to keep home win streak going, host the Cardinals

St. Louis Cardinals (47-40, third in the NL Central) vs. Pittsburgh Pirates (37-50, fifth in the NL Central) Pittsburgh; Wednesday, 12:35 p.m. EDT PITCHING PROBABLES: Cardinals: Sonny Gray (8-2, 3.36 ERA, 1.

Guardians aim to break 5-game skid, take on the Cubs

Cleveland Guardians (40-43, second in the AL Central) vs. Chicago Cubs (50-35, first in the NL Central) Chicago; Wednesday, 8:05 p.m. EDT PITCHING PROBABLES: Guardians: Tanner Bibee (4-8, 3.80 ERA, 1.

Rangers and Orioles play with series tied 1-1

Baltimore Orioles (37-48, fifth in the AL East) vs. Texas Rangers (42-44, fourth in the AL West) Arlington, Texas; Wednesday, 8:05 p.m. EDT PITCHING PROBABLES: Orioles: Tomoyuki Sugano (6-4, 4.06 ERA, 1.

Seattle Mariners square off against the Kansas City Royals Wednesday

Kansas City Royals (40-46, fourth in the AL Central) vs. Seattle Mariners (44-41, second in the AL West) Seattle; Wednesday, 9:40 p.m. EDT PITCHING PROBABLES: Royals: Noah Cameron (2-4, 2.79 ERA, 1.

Twins come into matchup against the Marlins on losing streak

Minnesota Twins (40-45, third in the AL Central) vs. Miami Marlins (38-45, third in the NL East) Miami; Wednesday, 6:40 p.m. EDT PITCHING PROBABLES: Twins: Simeon Woods Richardson (3-4, 4.63 ERA, 1.

Angels bring 1-0 series lead over Braves into game 2

Los Angeles Angels (42-42, third in the AL West) vs. Atlanta Braves (38-46, fourth in the NL East) Atlanta; Wednesday, 7:15 p.m. EDT PITCHING PROBABLES: Angels: Yusei Kikuchi (3-6, 2.79 ERA, 1.37 WHIP, 99 strikeouts); Braves: Didier Fuentes (0-2, 10.
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